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The MHRA states that it can help people feel fuller, reduce hunger and decrease food cravings when used as part of a structured weight management plan

Additionally, individuals who have experienced significant weight loss while taking semaglutide might require different sedative dosages than those who have maintained their weight, as their body composition and metabolism may have changed

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Randomized trials report 612 % body-weight loss at 56 weeks when Contrave is paired with lifestyle counseling (Wiley 2024)

But these changes can also be experienced with weight loss through diet and exercise