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Description

GLP-1RA FAERS analyses (class-level): FAERS analyses across GLP-1 receptor agonists highlight dehydration/volume depletion as an area needing attention and demonstrate sex differences in some adverse event patterns in broader AE categories

Overall, theoretically, differences in the pharmacokinetic profiles of different GLP-1RAs may have important implications for their efficacy in BAD and perhaps help explain why liraglutide could be superior in reducing symptoms of BAD as compared with the more potent and longer-acting semaglutide

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Among different polarization conditions (including Th1, Th2, Th17, and Treg polarization conditions), the expression level of GLP-1R was highest in CD4 + T cells under Treg polarization conditions, and the proportion of GLP-1R + cells could reach 29-34%