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Heartburn, also known as acid reflux, is a burning sensation in the chest that occurs when stomach acid flows back into your food pipe, causing discomfort, pain, and a sour taste in your mouth

Since the presence of albuminuria is related to increased kidney and cardiovascular risk, renin-angiotensin system (RAS) blockade is recommended in patients with diabetes, hypertension, and albuminuria

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Metabolism occurs via proteolytic degradation and fatty acid beta-oxidation, similar to other acylated peptides in this class