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Kidney function typically stays stable or improves with weight loss, but dehydration during rapid weight loss can temporarily lower kidney functionstaying hydrated and getting checked regularly prevents problems

The incidence of persistent, markedly low serum bicarbonate values (levels of less than 17 mEq/L on 2 consecutive visits or at the final visit) was 0.2% for QSYMIA 7.5 mg/46 mg dose and 0.7% for QSYMIA 15 mg/92 mg dose, compared to 0.1% for placebo

Drinking plenty of water and resting in a quiet, dark room may also provide relief

Myriad options such as manufacturer savings or copay assistance are explored to ensure attainable treatment for all clients

The study randomized participants to receive semaglutide 2.4 mg or placebo along with lifestyle modification for 68 weeks