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59 Although some effects of GLP-1 RAs, particularly weight loss, are linked to direct effects of GLP-1 RAs in brain areas responsible for appetite, satiety, food behaviour and other central regulatory mechanisms, data regarding the potential impact of therapy on mental health among HF patients are lacking

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A high fat diet alters the microbial composition and causes microglial activation and vagal afferent reorganization in the NTS [50, 51]

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