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Ania Jastreboff, MD, PhD Cards Professional Highlights About Research Clinical Care Professional Highlights About Research Clinical Care Professional Highlights Honors 8 National Awards 3 Yale School of Medicine Awards 1 Yale University Award Activities 190 Activities 2006 - Present 18 Countries Service 1 Committee 12 Professional Organizations Honors 8 National Awards 3 Yale School of Medicine Awards 1 Yale University Award Activities 190 Activities 2006 - Present 18 Countries Service 1 Committee 12 Professional Organizations Honors 8 National Awards 3 Yale School of Medicine Awards 1 Yale University Award Activities 190 Activities 2006 - Present 18 Countries Service 1 Committee 12 Professional Organizations Titles Professor of Medicine (Endocrinology) Director, Yale Obesity Research Center (Y-Weight) Co-Director, Yale Center for Weight Management Education Yale University Graduate School of Arts and Sciences, Investigative medicine (2012) University of Maryland at Baltimore (2002) Bucknell University, Art History/Major, Music/Minor

Some patients and clinicians prematurely conclude the medication is ineffective before reaching therapeutic doses of 10-15 mg weekly

By delaying digestion, Ozempic helps prevent post-meal blood glucose spikes and promotes sustained fullness, which aids glycaemic control and reduces appetite

NAD(+) repletion restores cardioprotective autophagy and mitophagy in obesity-associated heart failure by suppressing excessive trophic signaling

With intrinsic sympathomimetic activity (ISA) Pindolol Acebutolol Mechanism of Action Heart rate (negative chronotropy) Myocardial contractility (negative inotropy) AV nodal conduction Renin release from kidneys Overall: reduced cardiac workload and blood pressure Indications Cardiovascular Hypertension Ischemic heart disease (angina) Post-myocardial infarction Heart failure (metoprolol, bisoprolol, carvedilol) Arrhythmias (AF rate control, SVT) Non-cardiac Thyrotoxicosis Migraine prophylaxis Essential tremor Anxiety (performance anxiety) Portal hypertension (variceal bleed prophylaxis) Glaucoma (topical timolol) Adverse Effects Bradycardia Hypotension Fatigue Cold extremities Sexual dysfunction Sleep disturbances (esp