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A letter reported the clinical manifestations of the GLP-1RA exenatide in acute stroke patients for the first time, including treatment regimens and adverse reactions (107)

Clinicians should interpret preliminary findings with appropriate caution and await results from adequately powered randomized controlled trials before drawing firm conclusions about neuroprotective benefits

Associated with right upper quadrant abdominal pain , especially if accompanied by jaundice, dark urine, or pale stoolsthese symptoms may suggest gallbladder disease (cholecystitis or cholelithiasis), which occurs at increased rates with GLP-1 therapy

Entyvios performance last year was primarily driven by the successful launch of the Entyvio Pen for subcutaneous administration in the US, which touts to enhance patient convenience and adherence

Evidence based on recent studies Initially, cases of intestinal obstruction associated with GLP-1 RAs were reported by the European Medicines Agency (EMA) in 2013 [9], and this safety signal is currently being monitored by the United States (US) FDA