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The yerba mat extract was prepared by spray drying an aqueous extract of Ilex paraguariensis leaves and was provided to the animals per the manufacturers instructions (7.49 g yerba mat powder per 300 mL water)

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Management strategies include smaller frequent meals, texture modifications, adequate hydration, and gradual dose titration under medical supervision

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Black Box Warning GLP-1 receptor agonists, including semaglutide, carry a black box warning for the risk of thyroid C-cell tumors, based on findings in animal studies