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Nausea, vomiting, and other gastrointestinal symptoms are common, particularly when starting or increasing the dose and in T1D trials, these rates were similar to those seen in T2D and obesity trials

For someone who wants steady improvements and has tolerated GLP-1 receptor agonists before, Ozempic is a well-understood choice

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Dehydration amplifies the effects of blood loss, so drinking extra water is especially important if you're on a GLP-1 medication that may affect fluid retention

However, an anabolizing agent such as GLP1-RAs can also upregulate the AMPK-pathway, due to cAMP accumulation ( Figure 1 )