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The signal is real in the data, contested in its meaning, and still unresolved

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Plaintiffs allege that GLP-1 drugs can impair gastrointestinal motility by slowing gastric emptying and altering normal digestive function, which in some patients is claimed to progress into diagnosed disorders rather than short-term intolerance

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Using GLP-1 injections with lifestyle changes supports better outcomes

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Thus, the vagal sensory neurons that express the receptor and respond to the systemic administration of GLP-1R agonists do not synaptically target the hindbrain GLP-1 neurons

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