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The causative role of GLP-1 in T2DM remission after bariatric surgery will be difficult to tease apart in humans, but other predictive factors such as duration of disease, and thus the degree of -cell destruction before surgery, may be more critical in determining whether -cells can recover sufficiently to resolve T2DM (84)

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Sleep apnea Tirzepatide (Zepbound) is now FDA-approved for obesity with moderate to severe obstructive sleep apnea (OSA), a sleep disorder that causes low oxygen at night

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For patients with first-time anti-obesity medication prescriptions in March 2025, only 46.8% had evidence of a prescription fill within 60 days, compared to 72.2% of patients receiving anti-diabetic medication prescriptions

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Retatrutide could transform public health outcomes and potentially establish new benchmarks for obesity treatment

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