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Researchers are also investigating whether the drugs could be used to treat substance use disorders

Management depends on symptom severity and may range from lifestyle modifications and medications (proton pump inhibitors, antacids) to surgical repair in refractory or complicated cases

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Insulin resistance affects roughly 1 in 3 American adults and often drives both weight gain and difficulty losing weight

The new drugs "cover a major unmet need: obesity was one of the only chronic diseases for which there were few medications," said French endocrinologist Emmanuel Disse