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Lack of baseline measurements for liver steatosis and fibrosis before the initiation of the EDICT study, as well as the small number of patients enrolled were the main limitations of this trial
Further, the subscription cost can be prohibitive for some
Out-of-pocket costs are the strongest predictor of abandonment: High OOP costs drive non-adherence, especially in obesity, where coverage is limited and stigma persists
Patients should not rely on the medication alone
But also you could have decreased motivation to engage in physical activities and exercise
