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Rapid metabolic changes associated with semaglutide use have been associated with temporary worsening of pre-existing retinopathy in some patients

However, no members from the Korean Society for the Study of Obesity were present at the meeting

Metabolic and cardiometabolic markers that may reflect the drug's activity include: Fasting blood glucose and HbA1c (particularly relevant in type 2 diabetes) Lipid profile (total cholesterol, LDL, triglycerides) Blood pressure Waist circumference Liver function tests, particularly in patients with metabolic dysfunction-associated steatotic liver disease (MASLD, previously termed NAFLD)
