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Prevalence and trends in obesity among US adults, 1999-2008

As per Bradford Hills criteria 41 , the biological plausibility through GLP-1R expression in the nervous system and temporal consistency in time-to-onset analysis support potential causality, but confounding factors inherent to spontaneous reporting systems preclude definitive conclusions

One small study of humans showed that curcumin (1,500 mg daily) reduced weight and blood sugar in people with Type 2 diabetes

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Appetite suppression, while the desired therapeutic effect, can feel like an unpleasant side effect if you're not mentally prepared for it