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This is especially noted in patients who already have some degree of retinopathy when starting the medication
Clinical guidance recommends a lower-calorie plan, roughly 1,200 to 1,500 calories daily for most women and 1,500 to 1,800 for most men, combined with about 1 to 1.2 grams of protein per kilogram of body weight to protect muscle
For a market most Western pharma teams still treat as secondary, that's a striking number
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