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Like all medications, Semaglutide can have side effects
Because the upper limit of the two-sided 95% CI for the estimated differences was below 0 kg, superiority of SEM 0.5 mg or SEM 1 mg versus placebo in change in body weight was demonstrated

doi:10.1056/NEJMoa2410027 Nicholls SJ, Pavo I, Bhatt DL, et al

Participants were equally assigned to the two groups

The ACHIEVE-1 results will be presented at ADA's 85th Scientific Sessions and published in a peer-reviewed journal
