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A sample size of eight youth would have 80% power to detect a 10% difference in GPR and rate of fractional gluconeogenesis, = 0.05

The mechanism that slows gastric emptying, believed to cause gastroparesis, is present in both semaglutide and tirzepatide drugs

Any lung or breathing concerns that emerge during GLP-1 therapy should be evaluated by a doctor to identify the true causesuch as prior asthma, sleep apnea, or cardiovascular changesrather than assumed to be a medication effect

The reason this topic receives so much attention is the semaglutide cardiovascular outcomes trial SUSTAIN-6, in which diabetic retinopathy complications were reported more often in the semaglutide group than in the placebo group

The results suggest that GLP-1 drugs could offer a new option for the 48.4 million Americans with a substance use disorder