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However, other authors [80] have shown that the acute pharmacological activation or inhibition of AMPK had no effect on glucose sensing in VMH GE neurons

doi: 10.1158/1078-0432.CCR-21-0715 [DOI] [PMC free article] [PubMed] [Google Scholar] 136.Ishiguro N, Maeda K, Kishimoto W, et al

GLP-1 medications avoid this problem because they work on peripheral hormone systems that do not develop tolerance in the same way

Abdalqadir, N
