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Wegovy is also indicated to reduce excess body weight and maintain weight reduction long term in adults with obesity or adults with overweight and at least one weight-related comorbid condition

Gradual dose titration (starting at 3 mg for 30 days before increasing) and dietary modifications can significantly reduce gastrointestinal side effects

Studies found that of the additional 7.6-14.4% weight loss achieved with semaglutide versus placebo, less than 1 percentage point was mediated by gastrointestinal adverse events

Users concerned about muscle-related changes during GLP-1 therapy should prioritize strength training two to four times per week alongside any supplementation protocol

Several sections of the Good Laboratory Practice regulations specifically relate to laboratories