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This is especially relevant for older patients and those with significant weight to lose

This activation leads to reduced appetite, increased feelings of fullness after meals, and decreased food cravings

Its not about deprivation

Note also the ongoing concerns regarding sarcopenia in the elderly person with type 2 diabetes, which might be worsened by weight loss

Mapping the hepatic immune landscape identifies monocytic macrophages as key drivers of steatohepatitis and cholangiopathy progression
