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Pancreatitis The US Food and Drug Administration (FDA) and the European Medicines Agency highlighted concerns over whether incretin-based therapies may be damaging to the pancreas by conducting extensive studies

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(2) provided data on safety, pharmacokinetics, clinical management, or reproductive outcomes

Making a case for the combined use of SGLT2 inhibitors and GLP1 receptor agonists for cardiorenal protection

Semaglutide was also associated with reduced craving and drinks per day Data from participants daily logs indicated that those receiving semaglutide had less average alcohol craving each week (small effect size), and on average drank less drinks per drinking day while also having greater reductions in heavy drinking days over time (large effect sizes