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Fewer events in the placebo arm of SURMOUNT-1 compared with ONeil, STEP 1 and STEP 8 for total gastrointestinal AEs and nausea AEs suggest that the relative safety of tirzepatide versus liraglutide and semaglutide may be underestimated for these outcomes (see Supplementary Material Table S3)

Understanding this risk, recognizing early warning signs, and using personalized genetic testing can help you navigate tirzepatide therapy with confidence

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Of adults with prediabetes receiving tirzepatide who lost at least 5% of their body weight, up to 96% had a reversion to normoglycemia at 176 weeks vs