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Cumulative 36-month NAION incidence hit 8.9% in the diabetic semaglutide cohort versus 1.8% in comparators
SURPASS and SURMOUNT trials identified no cortisol dysregulation as either an adverse effect or a benefit (Bolt Pharmacy UK)

[DOI] [PubMed] [Google Scholar] 232.Unger RH, Aguilar-Parada E, Mller WA, Eisentraut AM

Although proposed mechanismssuch as modulation of the HPA axis and central GLP1 receptor signallingsuggest potential antidepressant effects, clinical findings remain inconsistent

Alcohol can irritate the stomach and increase your risk of nausea or low blood sugar, especially if youre eating less
