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Side effects: Nausea (most common, especially first weeks) Constipation Fatigue Food aversions (can be severe) Potential hair thinning (temporary) Learn how to manage these in our peptide safety and risks guide

Final Thoughts What are the positive effects of GLP-1

These findings suggest the potential for substantial glycaemic improvement in certain individuals, though results from a single phase 2 trial should be interpreted cautiously

One promising avenue of investigation involves pharmacotherapies that specifically target obesity

Notably, gut microbiome signatures were highly homogenous within all individual experimental groups, which may be ascribed to the application of paired fecal samples to reduce interindividual variability in combination with a stable phenotype