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This lower initial dose helps to minimize potential side effects

People who took Zepbound, Eli Lillys weight loss drug, shed more pounds than those on Novo Nordisks Wegovy in a head-to-head clinical trial, Lilly said in a news release Wednesday

The initial twice-daily formulation was discontinued due to exceptionally high rates of gastrointestinal adverse events (nausea and vomiting), leading to discontinuation rates exceeding 50% in trials

Nausea and vomiting create a choice point where people prioritise feeling better now over better results later

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