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S1A, K and M) were significantly higher in A5 and progressively decreased in groups A2-A4 compared with in A1

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One analysis of several hundred GLP-1 studies presented compelling evidence that they improve cognitive disorders, such as Alzheimers, substance-use disorders, such as alcohol, cocaine, and cannabis addiction, and mood and anxiety disorders, such as depression and bipolar disorder

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Novel therapeutic strategies such as metformin, ketogenic diet, glucagon-like peptide-1 receptor agonists, caloric restriction, and lifestyle modifications have demonstrated potential by improving insulin sensitivity and restoring metabolic balance