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This effect may be explained by a DPP-4 inhibitor-dependent reduction in intestinal lipoprotein production and consecutive lowering of circulating chylomicrons ( Side Effects of DPP-4 Inhibitors DPP-4 inhibitors have shown good safety- and tolerability profiles in the phase III clinical study programs and the most frequent adverse events observed were nasopharyngitis and skin lesions

Although no firm causality was demonstrated, and recent observational data are reassuring, it seems prudent to screen for depression and anxiety as common comorbidities in clinical practice [133, 143147]

Important Notice: Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease

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As these drugs gain notoriety because of their weight-loss side effects, both drugmakers' sales have grown significantly