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Lancet (London, England) , 406(10522), 29272944

[DOI] [PubMed] [Google Scholar] 57.Kadowaki T, Chin R, Ozeki A, Imaoka T, Ogawa Y
Nausea, diarrhea, decreased appetite, and occasional vomiting are the most common side effects

doi:10.2337/dc23-1791 105

In fact, the circulating half-life of GLP-1 was only 1.52 minutes in human subjects with diabetes, and they proposed that inhibitors of DPP-4 could maintain higher levels of intact active endogenous GLP-1 for therapeutic purposes (44)