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In a PPND study in rats, administration of 0, 15, 35, and 60 mg/kg/day ritonavir from GD 6 through PND 20 resulted in no developmental toxicity, at ritonavir systemic exposures greater than 10 times the exposure at the approved human dose of PAXLOVID

Some plaintiffs allege that prolonged use of semaglutide medications caused gastroparesis, sometimes referred to as a paralyzed stomach, where food remains in the stomach for extended periods because normal muscular contractions no longer function properly

The reaction is local, not systemic

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The primary concern is that prednisolone and Wegovy have opposing effects on several metabolic parameters