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1823 Immunization recommendations for adults with DM are summarized in Table 21

injection therapy is not convenient

Rising type 2 diabetes prevalence and need for glucosedependent insulin secretion led to exenatide development from Gila monster peptide

Current evidence supports ongoing GLP-1 therapy for cardiovascular risk reduction and glycemic control in these populations, making indefinite treatment medically sound rather than a failure to achieve independence

Subjects with diabetes, hyperprolactinaemia, HIV, cataracts, breast or prostate cancer, end-stage renal disease, cystic fibrosis, uncontrolled hypertension, abnormal haemoglobin or heamatocrit, or subjects using medications known to interfere with sex steroid synthesis or action were excluded