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Fortunately, a tolerated treatment dose window of 150 g daily or less of cotadutide was associated with fewer adverse effects and this facilitated its progress to Phase 2 where its marked beneficial metabolic effects were observed

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Mechanisms and Pathways of Anti-Inflammatory Activity of DPP-4 Inhibitors in Cardiovascular and Renal Protection

GLP analogs (other than lixisenatide) are contraindicated in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) or a family history of medullary thyroid carcinoma
