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On a similar note, GLP-1R modulates the consumption of cocaine and the motivation to consume cocaine later in the addiction cycle
doi: 10.1038/S41598-019-55524-W 116 O'NeilPMBirkenfeldALMcGowanBMosenzonOPedersenSDWhartonSet al

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The cardiovascular benefits, demonstrated in the SELECT trial showing reduced heart attack and stroke risk with semaglutide, actually argue in favor of continued use for people with cardiovascular risk factors