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[See Clinical Pharmacology (12.3).] Add-on Combination Therapy with Metformin A total of 701 patients with type 2 diabetes participated in a 24-week, randomized, double-blind, placebo-controlled study designed to assess the efficacy of JANUVIA in combination with metformin

Semaglutide is known for good stability, but the conservative recommendation is 28 days
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Spraying water directly onto the powder
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Population differences Clinical trial participants are carefully selected