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Oprah Winfrey spoke candidly about weight loss on CNN, days after her special about how GLP-1s are changing the narrative aired.

These data unveil a new central role for GIPR signaling and identify a potentially important cell type expressing both GLP-1R and GIPR upon which tirzepatide or other dual agonists may modulate DA homeostasis in the brain.

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Retatrutide and Mounjaro are both studied as weight loss medicines, but initial research suggests that retatrutide could cause more weight loss than Mounjaro.