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Long-term studies show that continuous drug dependence, gastrointestinal side effects, and rebound weight gain are common once treatment stops
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On Wegovy, patients lost an average of 17.4% of their body weight over the 68 week trial
However, discontinuation often leads to weight regain and loss of cardiometabolic benefits, 42 , 87 suggesting that, as with traditional antihypertensive drugs, sustained BP control may require ongoing use
10.1016/s0140-6736(09)60659-0 14 CampbellJ
