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We will examine the role of DPP-4 inhibitors in clinical practice Pharmacology In humans, two incretin peptide hormones have been identified

Recent studies have found that GLP-1RAs have therapeutic effects on neurological, cardiovascular, endocrine and metabolic diseases

The line between cosmetic and medical use can blur some criticize that celebrities or the very wealthy obtained Wegovy off-label just to drop a few pounds, leading to shortages for those with diabetes who needed Ozempic for health

Furthermore, GLP-1 RAs have beneficial effects for reducing the risk of MI or endpoints composed of coronary events (e.g., MACE, cardiovascular mortality), while solid evidence on CCS, vasospastic angina, and MVA is lacking

Endocrinology 149 (5), 20382047