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3 Recent reviews also highlight the dorsomedial hypothalamus as an important target for pre-ingestive cognitive satiation, alongside broader hypothalamic and hindbrain circuits that shape meal initiation, satiation, and satiety
Starting dose and titration speed also affect the timeline
If you notice any of these, get medical help right away
Sources Chamarthi, V
Contact your GP within 2448 hours if you experience headaches that progressively worsen despite simple painkillers, persist beyond 48 weeks of stable dosing, or significantly interfere with daily activities
