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Some people exceed clinical trial averages due to aggressive dietary modifications or exercise protocols

The entire value of the GLP-1 ID protocol depends on accurate, honest reporting

The dual agonism seems to lower hs-CRP levels about 30% more than GLP-1 mono-agonists do at the same amount of weight loss, which suggests that it has anti-inflammatory effects beyond just weight loss

If side effects persist or grow worse with each dose increase, clinicians usually slow escalation, reduce the dose, or suspend therapy while investigating other causes