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Objective: We aim to investigate if semaglutide is associated with a decreased risk of dementia

A meta-analysis further demonstrated that susceptibility variants in SLC30A8 and KCNJ11which affect insulin-granule zinc transport and KATP-channel activity, respectivelyalter insulinotropic responses, potentially modifying GLP-1-based therapeutic outcomes [73,74]

doi: 10.3389/fcvm.2025.1535134 Received 26 November 2024 Accepted 28 March 2025 Published 24 April 2025 Volume 12 - 2025 Edited by Preetha Shridas, University of Kentucky, United States Reviewed by Aneesh Dhore-patil, Houston Methodist Hospital, United States Raffaele Carraro, La Princesa University Hospital, Spain Updates Copyright 2025 Turkistani