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Description
For patients planning pregnancy, semaglutide should be discontinued at least 2 months before a planned pregnancy due to the long half-life, while tirzepatide may persist for approximately 1 month

Switching to transdermal estrogen may be a better option for those on oral hormone replacement therapy to avoid absorption issues

PMC 4020673

This is referred to as delayed gastric emptying

Once-weekly semaglutide in adults with overweight or obesity
