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2025 doi: 10.1001/jama.2025.11153

MDL 3094 In Re: Glucagon-like Peptide-1 Receptor Agonists (GLP-1 RAS) Products Liability Litigation

But as prescriptions climb, so do questions about safety, long-term use, and the risks of cheaper, unregulated alternatives

The analysis showed that GLP-1s containing tirzepatide (Zepbound, Mounjaro) helped people lose more weight than those containing semaglutide (Ozempic, Wegovy)
In addition, 37.0% of people treated with 2.4 mg semaglutide achieved improvements in liver fibrosis with no worsening of steatohepatitis compared to 22.5% on placebo
