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In the trials reporting discontinuation because of any adverse events and those specifically due to gastrointestinal side effects, the latter were responsible for approximately one-half of the withdrawals

As part of a holistic weight loss plan, it can help individuals achieve and maintain a healthier body weight over time, though results can vary depending on individual circumstances

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These agents work by activating the GLP-1R rather than inhibiting the breakdown of GLP-1, as do DPP-4 inhibitors, and are considered more potent (Table 1)