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Metformin, as the only biguanide, is likely her foundational diabetes medication, probably one of the first she was prescribed

While we usually associate this with adipose or fat tissue, excess fat is also stored in the muscle

Badjatiya A, Merrill P, Buse JB, Goodman SG, Katona B, Iqbal N, et al
Villumsen M et al

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