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The most recent understanding of this deficit suggests that it relates to deterioration of the GLP-1 effect, with impaired capacity to secrete insulin, increasing insulin resistance, and hyperglycemia, perhaps leading to a decrease in GLP-1 receptor expression and resulting in GLP-1 resistance (7)

This could contribute to the mentioned side effects of brain fog, mood swings, and even faster cognitive decline, which are some of the very issues we hope to prevent

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