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doi: 10.1093/eurheartj/ehz486 6 American Diabetes A

Clinical Significance: These data suggest that orforglipron could provide an oral alternative to injectable GLP-1 therapies

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When considering compounded GLP-1 options like semaglutide or tirzepatide, understanding your individual gastric physiology and genetic factors affecting appetite regulation may help provide context for a personalized safety conversation with your healthcare provider

Lastly, liraglutide has been shown to be able to affect the M1/M2 ratio, promoting an M2 phenotype in apoE / mice with an atheroprotective effect [63]