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Weight Loss Efficacy (Phase 2, 48 Weeks) * Retatrutide: Mean body weight reduction up to 24.2% * Eloralintide: Mean body weight reduction up to 20.1% Both agents place themselves among the most potent obesity therapies currently in clinical development.

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BMI Is GLP-1 right for me?* 24.9 or less No 25.0 29.9 Case-by-case 30.0 or above Likely *The above chart is not meant for medical diagnosis purposes

The two most abundant and prominent endocrine cell types, the beta and the alpha cells, are essential for the maintenance of blood glucose homeostasis