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can you combine glp 1 and dpp4 GLP-1-based therapies for type 2 diabetes: from single, dual triple agonists to endogenous GLP-1 production and L-cell differentiation | Diabetology & Metabolic Syndrome The Role of DPP-4 Inhibitors
Description
At baseline, the mean eGFR was 82 mL/min/1.73 m and 35% of patients had eGFR 90 mL/min/1.73 m
There have been cases where people developed a severe skin reaction called Stevens-Johnson syndrome
The mechanisms of these drugs, which include slowing gastric emptying and signaling fullness to the brain, work synergistically with a high-protein diet to enhance these effects
When that pathway is disrupted by obesity, aging, or poor diet GLP-1 production downstream suffers
Caveats: compounded-only, no FDA-approved brand-name path
