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Native GLP-1, GLP-1RAs and BBB Numerous studies have discovered the expression of native GLP-1 in CNS, implying that natural GLP-1 could cross the BBB from the peripheral circulation via passive transport due to their physiological, molecular biology, pharmacokinetic, and pharmacodynamic properties

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Access this article Similar content being viewed by others References Nissen SE, Wolski K

However, referral to an endocrinologist may be recommended if your thyroid condition is unstable or difficult to manage

Tirzepatide was initially approved for type 2 diabetes (Mounjaro), and it is now also approved for long-term weight loss in adults with obesity or overweight with weight-related health conditions (Zepbound)