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Hittel DS, Berggren JR, Shearer J, Boyle K, Houmard JA

The included studies can be seen in Table 1

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(Center) In macrophages, GLP-1 can significantly increase the expression of GLP-1 receptor through G protein-coupled receptor 119 (GPR119), enhance the activity of ABCA1, lead to the increase of apo AI, and thus promote intracellular cholesterol outflow

In the pancreas, they stimulate glucose-dependent insulin secretion and suppress glucagon release, improving glycemic control
